RESUMO
Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL-13, PD1 often BCL-6 and CD20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD21 and CD23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline-containing regimens.
Assuntos
Antineoplásicos/administração & dosagem , Neoplasias Pulmonares , Pulmão/diagnóstico por imagem , Radioterapia/métodos , Rabdomiossarcoma Alveolar , Adulto , Diagnóstico Diferencial , Evolução Fatal , Humanos , Biópsia Guiada por Imagem/métodos , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/fisiopatologia , Neoplasias Pulmonares/terapia , Masculino , Estadiamento de Neoplasias , Derrame Pleural/diagnóstico , Derrame Pleural/etiologia , Rabdomiossarcoma Alveolar/diagnóstico , Rabdomiossarcoma Alveolar/patologia , Rabdomiossarcoma Alveolar/fisiopatologia , Rabdomiossarcoma Alveolar/terapia , Toracentese/métodos , Tomografia Computadorizada por Raios X/métodosRESUMO
Merkel cell carcinomas (MCCs) are uncommon, highly malignant skin tumors that develop in sun-exposed areas of the skin. Most of the MCCs are CK 20-positive and CK 7-negative such as our case. About 80% of Merkel cell carcinoma is associated with Merkel cell polyomavirus.